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US IPO Week Ahead: Precision medicine and insurance IPOs take on the short holiday week

June 13, 2025
Week Ahead

Two sizable IPOs are scheduled to price in the short holiday week ahead.

Precision medicine platform Caris Life Sciences (CAI) plans to raise $400 million at a $5.2 billion market cap. The company is developing and commercializing a platform combining next-gen sequencing and AI/ML technologies for cancer diagnostics. Growing but highly unprofitable, Caris is targeting a large opportunity in the dynamic but increasingly crowded oncology market.

Florida-based insurer Slide (SLDE) plans to raise $320 million at a $2.2 billion market cap. Led by the founder and former CEO of Heritage Insurance, Slide operates in the residential property insurance market. It focuses on single-family homeowners, condominium owners, and other commercial residential properties, primarily on the coasts of Florida and South Carolina, which are exposed to significant hurricane risk.

U.S. IPO Calendar
Issuer
Business
Deal Size
Market Cap
Price Range
Shares Filed
Top
Bookrunners
Caris Life Sciences (CAI)
Irving, TX
$400M
$5,219M
$16 - $18
23,529,412
BofA
JP Morgan
Offers an AI-powered molecular diagnostics platform focused on oncology.
Slide (SLDE)
Tampa, FL
$320M
$2,247M
$15 - $17
20,000,000
Barclays
Morgan Stanley
Home insurance provider focused on the coastal southern US.
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Street research is expected for four companies in the week ahead, and four lock-up periods will be expiring. For access to Street research and lock-up expiration dates, sign up for a free trial of IPO Pro.

IPO Market Snapshot
The Renaissance IPO Indices are market cap weighted baskets of newly public companies. As of 6/12/2025, the Renaissance IPO Index was up 1.3% year-to-date, while the S&P 500 was up 3.4%. Renaissance Capital's IPO ETF (NYSE: IPO) tracks the index, and top ETF holdings include Arm Holdings (ARM) and Astera Labs (ALAB). The Renaissance International IPO Index was up 19.8% year-to-date, while the ACWX was up 17.2%. Renaissance Capital’s International IPO ETF (NYSE: IPOS) tracks the index, and top ETF holdings include Galderma and Amman Mineral.