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US IPO Weekly Recap: Asthma-focused Generate Biomedicines closes out February IPO market

February 27, 2026
Weekly Recap

One IPO and six SPACs came to market this past week, and one major issuer joined the pipeline as February comes to a close.

Generate Biomedicines (GENB) priced its IPO at the midpoint to raise $400 million at a $2.2 billion market cap. The Flagship Pioneering-incubated biotech is using its AI platform, which combines programmable capabilities with biohardware and data, to develop drugs with both precision and scale. Its most advanced candidate is in Phase 3 trials for severe asthma. Generate finished down 21%.

The week’s six blank check IPOs were led by MOZAYYX Acquisition (MZYX.U), which raised $261 million to target fintech, energy, cybersecurity, and other high-growth areas.

7 IPOs During the Week of February 23rd, 2026
Issuer
Business
Deal
Size
Market Cap
at IPO
Price vs.
Midpoint
First Day
Return
Return
at 02/27
Fortress Value Acq. V (FVAV)$250M$315M0%+0%+0%
Sixth blank check company by executives at Fortress Investment Group.
TRG Latin America Acq. (TRGSU)$200M$252M0%+0%+0%
Blank check company led by Nicolas Rohatyn focused on Argentina and greater Latin America.
APEX Tech Acquisition (TRADU)$100M$146M0%n/a+0%
Blank check company formed by Chinese manufacturing executives targeting US businesses.
ClearThink 1 Acquisition (CTAAU)$125M$170M0%+0%+0%
Blank check company backed by ClearThink Capital targeting financial services in the US and other developed countries.
MOZAYYX Acquisition (MZYX.U)$261M$326M0%+0%+0%
Blank check company targeting fintech, energy, cybersecurity, and other high-growth areas.
Illumination Acq. I (ILLUU)$200M$272M0%-1%-1%
Blank check company formed by Lucid Capital Markets executives.
Generate Biomedicines (GENB)$400M$2,249M0%-21%-21%
Phase 3 biotech using AI to develop therapies for immunology and oncology.
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Three IPOs submitted initial filings this week, led by Healthpeak Properties’ senior housing REIT Janus Living (JAN), which we estimate could raise up to $500 million. They were joined by a direct listing, Canada-based The Metals Royalty Co. (TMCR).

Two SPACs also submitted initial filings. RMG ML Sports Holdings (SHOTU) plans to raise $261 million, and Dune Acquisition III (DUNU.RC) plans to raise $150 million.

6 Filings During the Week of February 23rd, 2026
Issuer
Business
Deal
Size
SectorLead
Underwriter
Janus Living (JAN)$500MReal EstateBofA
Senior housing REIT being carved out of Healthpeak Properties.
RMG ML Sports Holdings (SHOTU)$261MSPACSantander
Blank check company led by Riverside's James Carpenter targeting sports.
The Metals Royalty Co. (TMCR)$0MMaterials 
Canadian critical metals and mineral royalty acquirer with one asset in the Pacific Ocean.
UDynamics (UDUD)$18MTechnologyPacific Century
Hong Kong-based provider of web hosting, cloud, and IT services.
Guardian Metal Resources (GMTL)$50MMaterialsBMO
Tungsten-focused exploration-stage mining company with projects in Nevada.
Dune Acquisition III (DUNU.RC)$150MSPACClear Street
Blank check company targeting digital assets, sports and entertainment, SaaS, and AI.
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IPO Market Snapshot

The Renaissance IPO Indices are market cap weighted baskets of newly public companies. As of 2/26/2026, the Renaissance IPO Index was down 0.6% year-to-date, while the S&P 500 was up 1.1%. Renaissance Capital's IPO ETF (NYSE: IPO) tracks the index, and top ETF holdings include CoreWeave (CRWV) and Kenvue (KVUE). The Renaissance International IPO Index was up 16.4% year-to-date, while the ACWX was up 11.2%. Renaissance Capital’s International IPO ETF (NYSE: IPOS) tracks the index, and top ETF holdings include Kioxia and Galderma.