Biotech IPOs just capped off their biggest month in 5+ years.
Four drug developers raised a combined $1.5 billion in April, the most biotech proceeds since March 2021.
Biotech deal flow was weak in recent years, but the space is now on a roll. This week’s three biotechs all upsized, priced high, and surged on day one. All three had candidates in Phase 2 or later, and ranged from blood clotting (COAG), respiratory disease (AVLN), and depression (SPTX).
Beyond biotechs, April was a solid month for new issuance – and the biggest month for new filings in over four years. The growing pipeline should translate to a more robust pickup through the rest of Q2. For now, new IPO filings are taking a short breather as companies finalize their Q1 numbers.
The May IPO market is slated to kick off with radio signal analyzer HawkEye 360 (NYSE: HAWK) and beverage brand Suja Life (Nasdaq: SUJA). HawkEye is the latest issuer tapping into demand for defense tech, while Suja will test demand for fast-growing consumer brands.
Looking ahead, investors are still anxiously awaiting SpaceX's public filing, which could land in a few weeks assuming a June launch. Another mega-IPO in the wings, OpenAI, reportedly missed internal growth targets. The company disputed the report, but there’s now more speculation that a 2027 IPO is more likely.
Non-traditional IPOs had a big week. Bill Ackman’s closed-end fund, Pershing Square USA (NYSE: PSUS), raised $5 billion but began trading at a clear discount to NAV. His management company Pershing Square (NYSE: PS) also listed directly with a $10+ billion valuation. Meanwhile, new SPAC activity surged as 11 deals raised $2.2 billion.
The IPO Index ended the week flat, compared to a +0.9% return for the S&P 500. Marketing software provider Klaviyo was the winner, up +14.1%. Hospital billing platform Waystar landed at the bottom, off -17.6%.
Take care,
Bill Smith
CEO and Founder
Renaissance Capital
|
Biggest price changes through
May 1st
in the
Renaissance IPO Index
|
||
|---|---|---|
| Top 5 | ||
| Klaviyo | KVYO | 14.1% |
| Figure Technology Solutions | FIGR | 13.4% |
| Legence | LGN | 12.1% |
| Forgent Power Solutions | FPS | 11.6% |
| Netskope | NTSK | 9.2% |
| Bottom 5 | ||
| Waystar Holding | WAY | -17.6% |
| Atmus Filtration Technologies | ATMU | -15.4% |
| EquipmentShare.com | EQPT | -12.4% |
| Smithfield Foods | SFD | -10.4% |
| Arm Holdings | ARM | -10.1% |
| Sectors | ||
| Financials | 3.2% | |
| Energy | 1.9% | |
| Technology | 0.8% | |
| Industrials | -0.1% | |
| Real Estate | -1.5% | |
| Health Care | -1.5% | |
| Consumer Discretionary | -2.2% | |
| Consumer Staples | -5.4% | |
Renaissance IPO ETF (NYSE symbol: IPO) tracks the Renaissance IPO Index
The Renaissance IPO Index returned 0.0% last week vs. 0.9% for the S&P 500.

