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US IPO Weekly Recap: CRISPR biotech pops 44% as more names join the IPO pipeline

July 24, 2026
Weekly Recap

One IPO priced this past week, joined by four SPACs.

Cardiovascular disease biotech Scribe Therapeutics (SCTX) upsized and priced at the high end to raise $129 million at a $273 million market cap. Scribe is developing in vivo CRISPR-based therapies, with an initial focus on cardiovascular and metabolic disease. Its lead candidate uses an epigenetic silencing approach to durably lower LDL-C by repressing PCSK9 expression, without permanently altering DNA. It's currently in a first-in-human trial in Australia under TGA clearance, with initial data expected in the first half of 2027. Scribe popped 44%.

5 IPOs During the Week of July 20th, 2026
Issuer
Business
Deal
Size
Market Cap
at IPO
Price vs.
Midpoint
First Day
Return
Return
at 07/24
Scribe Therapeutics (SCTX)$129M$273M7%+44%+44%
Phase 1 biotech developing CRISPR genetic therapies for high cholesterol.
Southern Cross Acq. I (NCOOU)$100M$128M0%+0%+0%
Blank check company targeting businesses with industry leadership and revenue visibility.
Pelican Acquisition II (PLCIU)$75M$106M0%+0%+0%
Blank check company targeting the technology industry.
Market Technology Acq. (MTAKU)$200M$274M0%+0%+0%
Blank check company targeting US equities and options clearing infrastructure.
B&R Technology Merger (BRTMU)$325M$440M0%+0%-1%
Blank check company led by venture capitalist David York focused on tech companies with AI tailwinds.
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Two sizable issuers joined the IPO pipeline, led by defense tech firm Lyntris (LYNX), which filed for an estimated $300 million offering.

7 Filings During the Week of July 20th, 2026
Issuer
Business
Deal
Size
SectorLead
Underwriter
Bluerock Acquisition II (BRRKU)$150MSPACBTIG
Blank check company backed by Bluerock targeting Web3 businesses.
K2 Capital Acquisition II (KIIU)$150MSPACD. Boral Capital
Blank check company targeting national defense and critical infrastructure.
Lyntris (LYNX)$300MIndustrialsEvercore ISI
Provides defense tech connectivity solutions for military operations.
NorthStrive Acquisition I (NOSU.RC)$100MSPACD. Boral Capital
Blank check company targeting manufacturing companies.
Pinnacle Acquisition (PNAQ.U)$200MSPACSantander
Blank check company targeting commercial and consumer finance businesses.
Gravitics (GVTX)$125MIndustrialsLucid Cap. Mkts.
Develops large space structures and orbital systems.
TCGX Acquisition (TCGX)$75MSPACJefferies
Blank check company formed by TCGX executives targeting healthcare in Asia.
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IPO Market Snapshot
The Renaissance IPO Indices are market cap weighted baskets of newly public companies. As of 7/23/2026, the Renaissance IPO Index was up 16.7% year-to-date, while the S&P 500 was up 8.9%. Renaissance Capital's IPO ETF (NYSE: IPO) tracks the index, and top ETF holdings include Astera Labs (ALAB) and CoreWeave (CRWV). The Renaissance International IPO Index was up 38.7% year-to-date, while the ACWX was up 12.9%. Renaissance Capital’s International IPO ETF (NYSE: IPOS) tracks the index, and top ETF holdings include Galderma and CATL.