Squarex Pharmaceutical, a Phase 2 biotech developing a topical therapy for cold sores, filed on Tuesday with the SEC to raise up to $15 million in an initial public offering.
In its Phase 2 trial, the company's primary candidate, SQX770, was able to cut the number of cold sore outbreaks by 2.6-fold in the period from 42 to 120 days after a single topical dose on the arm, but failed to meet the planned primary endpoint. It has since completed an End-of-Phase 2 meeting with the FDA where it was established that two new toxicology studies in nonhuman animals, a two-dose bridging Phase 2 study, and two Phase 3 trials with about 900 patients would be required before reaching approval.
The Saint Paul, MN-based company was founded in 2012 and plans to list on the Nasdaq under the symbol SQRX. EF Hutton is the sole bookrunner on the deal. No pricing terms were disclosed.
