Merus Priced, Nasdaq: MRUS

Developing bispecific antibody treatments for solid tumors.

Industry: Health Care

Latest Trade: $25.00 0.00 (0.0%)

First Day Return: +0.4%

Return from IPO: +150.0%

Industry: Health Care

We are a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics. Our pipeline of full-length human bispecific antibody candidates, which we refer to as Biclonics, are generated from our technology platform. By binding to two different antigens, or targets, Biclonics can be designed to simultaneously block receptors that drive tumor cell growth and survival and to mobilize the patient’s immune response by activating various killer cells to eradicate tumors. In our pre-clinical studies, our bispecific antibody candidates were effective in killing tumor cells, a result that we believe supports their potential efficacy in the treatment of cancer. In February 2015, we commenced a Phase 1/2 clinical trial of our lead bispecific antibody candidate, MCLA-128, for the treatment of HER2-expressing solid tumors, and we expect to report top-line results from this trial in the second half of 2017. In May 2016, we commenced a Phase 1/2 clinical trial of our second bispecific antibody candidate, MCLA-117, for the treatment of acute myeloid leukemia, or AML. We are also developing MCLA-158, a bispecific antibody candidate that is designed to bind to cancer stem cells expressing leucine-rich repeat-containing G protein-coupled receptor 5, or Lgr5, and epidermal growth factor receptors for the potential treatment of colorectal cancer, and plan to submit an Investigational New Drug application to the U.S. Food and Drug Administration by the end of 2017 to initiate a Phase 1/2 clinical trial in the United States.
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IPO News for Merus
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IPO Data
IPO File Date 10/19/2015
Offer Price $10.00
Price Range $14.00 - $16.00
Offer Shares (mm) 5.5
Deal Size ($mm) $55
IPO Data
IPO Date 05/18/2016
Offer Price $10.00
Price Range $14.00 - $16.00
Offer Shares (mm) 5.5
Deal Size ($mm) $55
Underwriters
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Company Data
Headquarters Utrecht, Netherlands
Founded 2003
Employees 45
Website www.merus.nl