Aduro Biotech Priced, Nasdaq: ADRO

Developing two immunotherapy platforms for pancreatic and other cancers.

Industry: Health Care

Latest Trade: $11.30 -0.05 (-0.4%)

First Day Return: +147.1%

Return from IPO: -33.2%

Industry: Health Care

We are a clinical-stage immuno-oncology company focused on the development of first-in-class technology platforms designed to stimulate robust and durable immune responses against cancer, and our lead product candidate is in a randomized controlled Phase 2b clinical trial in metastatic pancreatic cancer. We intend to pursue a broad strategy of combining our technology platforms with conventional and novel immuno-oncology therapies, based on their mechanisms of action, safety profiles and versatility. Our pipeline of immuno-oncology product candidates is derived from two proprietary technology platforms: Live, Attenuated, Double-Deleted, Listeria monocytogenes and cyclic dinucleotides. Our lead LADD product candidate, CRS-207, is currently being developed in metastatic pancreatic cancer and unresectable malignant pleural mesothelioma. In a completed randomized controlled Phase 2a clinical trial in metastatic pancreatic cancer patients, CRS-207 demonstrated a statistically significant improvement in overall survival when combined with GVAX Pancreas, a cellular vaccine product candidate. The 93-patient two-arm Phase 2a clinical trial compared the combination of CRS-207 and GVAX Pancreas versus GVAX Pancreas alone. The trial met the primary efficacy endpoint of overall survival at an interim analysis and was stopped upon recommendation from the Data Monitoring Committee. Our lead immuno-oncology regimen of CRS-207 and GVAX Pancreas was granted Breakthrough Therapy and orphan drug designations by the FDA. We are developing a pipeline of proprietary product candidates, including two product candidates in collaboration with Janssen Biotech targeting prostate and lung cancers. In addition, we established a worldwide collaboration with Novartis Pharmaceuticals for CDN product candidates in oncology.
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IPO News for Aduro Biotech
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IPO Data
IPO File Date 03/11/2015
Offer Price $17.00
Price Range $17.00 - $17.00
Offer Shares (mm) 7.0
Deal Size ($mm) $119
IPO Data
IPO Date 04/14/2015
Offer Price $17.00
Price Range $17.00 - $17.00
Offer Shares (mm) 7.0
Deal Size ($mm) $119
Underwriters
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Company Data
Headquarters Berkeley, CA
Founded 2000
Employees 53
Website www.aduro.com